The Role of Retinoic Acid in Establishing the Early Limb Bud
Retinoic acid (RA) was one of the first molecules in the modern scissor era of experimental embryology to be shown capable of generating profound effects on limb development.In this review, we focus on the earliest events of limb development and specifically on the role of RA in establishing the domain of cells that will go on to Diet form the limb